Andrew;
Here it may be gov't fuding that drives a lot of research. In North America, it's private industry, primarily pharmecuticals and cosmetics in the private universities (numerically the higher number of institutions). Prior to moving here I was part of a private university that was essentially funding their science department on three major legs, Amgen (phramecuticals and clonng) Revlon (cosmetics) and the genome project (partnership of public and private funding). In the publicly funded education sector, this changes with more government driven research funding.
Part of my job description there was the safety and hazmat side of the process..... the only mostly clean & green group were the genome mapping folks. All they really required were massive server and UPS resources... As you indicate, the desire for the appropriate outcomes to fit the research model....... was important. The fear was always if it didn't fit, the funding would go away.
As an aside, my association with that particular organization wasn't very long when I began asking the inconvienient questions

.
It's a problem that has existed since science was called alchemy in one form or another in varying degrees. I don't have any answers, just observations from the basement...
Cheers
NoPolys
"Everyone is entitled to their own opinion, but not their own facts." - Daniel Patrick Moynihan-
"There are two kinds of people in the world: Those who can infer concepts from incomplete information." -unknown-